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Biglycan Protein (BGN) (Fc Tag)

This Recombinant Biglycan protein is expressed in HEK-293 Cells.
产品编号 ABIN7320153
发货至: 中国

Quick Overview for Biglycan Protein (BGN) (Fc Tag) (ABIN7320153)

抗原

See all Biglycan (BGN) 蛋白
Biglycan (BGN)

蛋白类型

Recombinant

宿主

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小鼠

资源

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HEK-293 Cells

纯度

> 85 % as determined by SDS-PAGE
  • 标记

    This Biglycan protein is labelled with Fc Tag.

    原理

    Recombinant Mouse Biglycan/BGN Protein (Fc Tag)

    序列

    Met1-Lys369

    产品特性

    A DNA sequence encoding the mouse BGN (Met1-Lys369) was expressed with the Fc region of human IgG1 at the C-terminus.

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Biglycan (BGN)

    别名

    Biglycan/BGN

    背景

    Background: Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.

    Synonym: BG,DSPG1,PG-S1,PGI,SLRR1A

    分子量

    66.5 kDa

    NCBI登录号

    NP_031568

    途径

    Glycosaminoglycan Metabolic Process
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