Biglycan Protein (BGN) (Fc Tag)
Quick Overview for Biglycan Protein (BGN) (Fc Tag) (ABIN7320153)
抗原
See all Biglycan (BGN) 蛋白蛋白类型
宿主
资源
纯度
-
-
标记
- This Biglycan protein is labelled with Fc Tag.
-
原理
- Recombinant Mouse Biglycan/BGN Protein (Fc Tag)
-
序列
- Met1-Lys369
-
产品特性
- A DNA sequence encoding the mouse BGN (Met1-Lys369) was expressed with the Fc region of human IgG1 at the C-terminus.
-
内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Please refer to the printed manual for detailed information.
-
缓冲液
- Lyophilized from sterile PBS, pH 7.4
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- Biglycan (BGN)
-
别名
- Biglycan/BGN
-
背景
-
Background: Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.
Synonym: BG,DSPG1,PG-S1,PGI,SLRR1A
-
分子量
- 66.5 kDa
-
NCBI登录号
- NP_031568
-
途径
- Glycosaminoglycan Metabolic Process
抗原
-