BCL2L2 Protein (His tag)
Quick Overview for BCL2L2 Protein (His tag) (ABIN7318198)
抗原
See all BCL2L2 蛋白蛋白类型
宿主
资源
纯度
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标记
- This BCL2L2 protein is labelled with His tag.
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原理
- Recombinant Human BCL-W/BCL2L2 Protein (His Tag)
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序列
- Ala2-Thr172
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产品特性
- Recombinant Human B Cell Lymphoma/Leukemia w is produced by our E.coli expression system and the target gene encoding Ala2-Thr172 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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BCL2-Like 2 (BCL2L2) (AA 1-172) protein (His tag)
BCL2L2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
BCL2-Like 2 (BCL2L2) (AA 1-193) protein (GST tag)BCL2L2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
BCL2-Like 2 (BCL2L2) (AA 2-193) protein (His-SUMO Tag)BCL2L2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 25 mM HEPES, 100 mM KCl, 20 % Glycerol, pH 7.5.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- BCL2L2 (BCL2-Like 2 (BCL2L2))
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别名
- BCL-W/BCL2L2
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背景
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Background: Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
Synonym: Bcl-2-Like Protein 2, Bcl2-L-2, Apoptosis Regulator Bcl-W, BCL2L2, BCLW, KIAA0271
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分子量
- 19.9 kDa
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UniProt
- Q92843
抗原
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