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ANGPTL4 Protein (Fc Tag)

ANGPTL4 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320470
发货至: 中国
  • 抗原 See all ANGPTL4 蛋白
    ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 7
    • 3
    • 3
    • 3
    • 1
    小鼠
    资源
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This ANGPTL4 protein is labelled with Fc Tag.
    原理
    Recombinant Mouse ANGPTL4 Protein (Fc Tag)
    序列
    Lys167-Ser410
    产品特性
    Recombinant Mouse Angiopoietin Like protein 4 is produced by our Mammalian expression system and the target gene encoding Lys167-Ser410 is expressed with a Fc tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ANGPTL4 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
    别名
    ANGPTL4 (ANGPTL4 产品)
    别名
    ANGPTL2 Protein, ARP4 Protein, FIAF Protein, HFARP Protein, NL2 Protein, PGAR Protein, pp1158 Protein, Arp4 Protein, Bk89 Protein, Fiaf Protein, Hfarp Protein, Ng27 Protein, Pgar Protein, Pgarg Protein, Pp1158 Protein, ANGPTL4 Protein, fiaf Protein, im:7144703 Protein, si:rp71-39b20.7 Protein, angiopoietin like 4 Protein, angiopoietin-like 4 Protein, ANGPTL4 Protein, Angptl4 Protein, angptl4 Protein
    背景

    Background: Angiopoietin-related protein 4(ANGPTL4)is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

    Synonym: Angiopoietin-related protein 4,425O18-1,Angiopoietin-like protein 4,Fasting-induced adipose factor,Hepatic fibrinogen/angiopoietin-related protein,HFARP,Secreted protein Bk89,Angptl4,Farp, Fiaf, Ng27

    分子量
    54.6 kDa
    UniProt
    Q9Z1P8
    途径
    Regulation of Lipid Metabolism by PPARalpha
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