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ACO2 Protein (His-GST)

This Recombinant ACO2 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7194100
发货至: 中国
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Quick Overview for ACO2 Protein (His-GST) (ABIN7194100)

抗原

See all ACO2 蛋白
ACO2 (Aconitase 2, Mitochondrial (ACO2))

蛋白类型

Recombinant

宿主

  • 7
  • 1
  • 1
人

资源

  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Baculovirus infected Insect Cells

纯度

> 85 % as determined by reducing SDS-PAGE.
  • 标记

    This ACO2 protein is labelled with His-GST.

    原理

    Recombinant Human ACO2/Aconitase 2 Protein (His & GST Tag)

    序列

    Gln 28-Gln 780

    产品特性

    A DNA sequence encoding the human ACO2 (Q99798) (Gln 28-Gln 780) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0, 0.3 mM DTT
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存液

    Dithiothreitol (DTT)

    注意事项

    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    ACO2 (Aconitase 2, Mitochondrial (ACO2))

    别名

    ACO2/Aconitase 2

    背景

    ACONM,ICRD,Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 receptor. IL10RB/IL-10RB belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB/IL-10RB are the cause of inflammatory bowel disease type 25 (IBD25). It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous, it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers, fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints.

    分子量

    Calculated MW: 110 kDa

    Observed MW: 110 kDa

    基因ID

    50

    UniProt

    Q99798
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