HPD Protein (His tag)
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北京 101111
Quick Overview for HPD Protein (His tag) (ABIN7318119)
抗原
See all HPD 蛋白蛋白类型
宿主
资源
纯度
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标记
- This HPD protein is labelled with His tag.
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原理
- Recombinant Human HPD/4HPPD Protein (His Tag)
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序列
- Met 1-Met393
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产品特性
- Recombinant Human 4-Hydroxyphenylpyruvate Dioxygenase is produced by our E.coli expression system and the target gene encoding Met1-Met393 is expressed with a 6His tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 1-393) protein (His-IF2DI Tag)
HPD 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 1-393) protein (GST tag)HPD 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
4-Hydroxyphenylpyruvate Dioxygenase (HPD) (Transcript Variant 2) protein (His tag)HPD 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
4-Hydroxyphenylpyruvate Dioxygenase (HPD) protein (Myc-DYKDDDDK Tag)HPD 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 1 mM DTT, 20 % Glycerol, pH 8.0.
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储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))
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别名
- HPD/4HPPD
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背景
- 4-Hydroxyphenylpyruvate Dioxygenase,4-Hydroxyphenylpyruvic Acid Oxidase,4HPPD,HPD,HPPDase,PPD,4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in high levels of tyrosine concentration in the blood, which can cause mild mental retardation at birth, and degradation in vision as a patient grows older.
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分子量
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Calculated MW: 47.1 kDa
Observed MW: 40-50 kDa
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基因ID
- 3242
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UniProt
- P32754
抗原
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