HPD Protein (His tag)
Quick Overview for HPD Protein (His tag) (ABIN7318119)
抗原
See all HPD 蛋白蛋白类型
宿主
资源
纯度
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标记
- This HPD protein is labelled with His tag.
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原理
- Recombinant Human HPD/4HPPD Protein (His Tag)
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序列
- Met 1-Met393
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产品特性
- Recombinant Human 4-Hydroxyphenylpyruvate Dioxygenase is produced by our E.coli expression system and the target gene encoding Met1-Met393 is expressed with a 6His tag at the N-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 1-393) protein (His tag)
HPD 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
4-Hydroxyphenylpyruvate Dioxygenase (HPD) (AA 1-393) protein (GST tag)HPD 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
4-Hydroxyphenylpyruvate Dioxygenase (HPD) (Transcript Variant 2) protein (His tag)HPD 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
4-Hydroxyphenylpyruvate Dioxygenase (HPD) protein (Myc-DYKDDDDK Tag)HPD 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 50 mM NaCl, 1 mM DTT, 0.1 mM PMSF, pH 8.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))
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别名
- HPD/4HPPD
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背景
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Background: 4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in high levels of tyrosine concentration in the blood, which can cause mild mental retardation at birth, and degradation in vision as a patient grows older.
Synonym: 4-Hydroxyphenylpyruvate Dioxygenase, 4-Hydroxyphenylpyruvic Acid Oxidase, 4HPPD, HPD, HPPDase, HPD, PPD
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分子量
- 47.1 kDa
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UniProt
- P32754
抗原
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