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SSTR2 Protein-VLP

SSTR2 宿主: 人 宿主: HEK-293 Cells VLP >80 % as determined by SDS-PAGE.
产品编号 ABIN7199157
发货至: 中国
  • 抗原 See all SSTR2 蛋白
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    蛋白类型
    VLP
    宿主
    • 10
    • 1
    资源
    • 5
    • 3
    • 2
    • 1
    HEK-293 Cells
    原理
    Human SSTR2 Full Length Protein-VLP (HEK293)
    序列
    Met 1 - Ile 369
    产品特性
    Human SSTR2 Full Length Protein-VLP is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ile 369 (Accession # P30874-1).
    纯度
    >80 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    组件
    Virus-like particles(VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrance Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.
    The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.
    Top Product
    Discover our top product SSTR2 蛋白
  • 应用备注
    The protein has a calculated MW of 45.3 kDa.
    说明

    Virus-like particles (VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrance Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.
    The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4
    储存条件
    -80 °C
    储存方法
    -70°C
  • 抗原
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    别名
    SSTR2 Protein-VLP (SSTR2 产品)
    别名
    Smstr2 Protein, SSTR-2 Protein, Smstr-2 Protein, sst2 Protein, SS2R Protein, SSTR2 Protein, MGC80373 Protein, somatostatin receptor 2 Protein, somatostatin receptor 2 L homeolog Protein, SSTR2 Protein, Sstr2 Protein, sstr2.L Protein
    背景
    Synonyms: Smstr2,Somatostatin R2,somatostatin receptor 2,somatostatin receptor type 2,SomatostatinR2,SRIF-1,SS2R,SS-2-R,SS2-R,SST2,SSTR2,
    Somatostatin is a peptide with a potent and broad antisecretory action, which makes it an invaluable drug target for the pharmacological management of pituitary adenomas and neuroendocrine tumors. Somatostatin receptors (SSTR1, 2A and B, 3, 4 and 5) belong to the G protein coupled receptor family and have a wide expression pattern in both normal tissues and solid tumors. Investigating the function of each SSTR in several tumor types has provided a wealth of information about the common but also distinct signaling cascades that suppress tumor cell proliferation, survival and angiogenesis. This provided the rationale for developing multireceptor-targeted somatostatin analogs and combination therapies with signaling-targeted agents such as inhibitors of the mammalian (or mechanistic) target of rapamycin (mTOR). The ability of SSTR to internalize and the development of rabiolabeled somatostatin analogs have improved the diagnosis and treatment of neuroendocrine tumors.
    分子量
    45.3 kDa
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