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CD38 Protein (Fc-Avi Tag,Biotin)

This Recombinant CD38 protein is expressed in HEK-293 Cells.
产品编号 ABIN7199090
发货至: 中国

Quick Overview for CD38 Protein (Fc-Avi Tag,Biotin) (ABIN7199090)

抗原

See all CD38 蛋白
CD38

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

纯度

>95 % as determined by SDS-PAGE.

质量等级

MALS verified
  • 标记

    This CD38 protein is labelled with Fc-Avi Tag,Biotin.

    原理

    Biotinylated Human CD38 Protein, Fc,Avitag™ (MALS verified)

    序列

    Val 43 - Ile 300

    产品特性

    Biotinylated Human CD38, Fc,Avitag (CD8-H82F5) is expressed from human 293 cells (HEK293). It contains AA Val 43 - Ile 300 (Accession # P28907-1).

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 136,947.45 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 172,528.32 ¥

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  • 应用备注

    This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 58.0 kDa. The protein migrates as 65-75 kDa under reducing (R) condition due to glycosylation.

    说明

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    CD38

    背景

    Synonyms: CD38,T10,cADPr hydrolase 1,
    Description: CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.

    分子量

    58.0 kDa

    NCBI登录号

    NP_001766
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