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CCR5 Protein-VLP

This VLP CCR5 protein is expressed in HEK-293 Cells.
产品编号 ABIN7199042
发货至: 中国
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Quick Overview for CCR5 Protein-VLP (ABIN7199042)

抗原

See all CCR5 蛋白
CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

蛋白类型

VLP

宿主

  • 10
  • 4
  • 1
  • 1

资源

  • 6
  • 5
  • 2
  • 1
HEK-293 Cells
  • 原理

    Human CCR5 Full Length Protein-VLP (HEK293)

    序列

    Met 1 - Leu 352

    产品特性

    Human CCR5 Full Length Protein-VLP (CC5-H52P3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Leu 352 (Accession # P51681-1).

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 150,642.20 ¥

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  • 应用备注

    The protein has a calculated MW of 40.5 kDa.

    说明

    Virus-like particles (VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrance Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.
    The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4

    储存条件

    -80 °C

    储存方法

    -70°C
  • 抗原

    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

    别名

    CCR5

    背景

    Synonyms: CCR5,CMKBR5,CD195,CC-CKR-5,CHEMR13,
    Description: Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.

    分子量

    40.5 kDa

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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