Topoisomerase II alpha Protein (AA 1354-1473)
Quick Overview for Topoisomerase II alpha Protein (AA 1354-1473) (ABIN7013599)
抗原
See all Topoisomerase II alpha (TOP2A) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 1354-1473
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序列
- AA 1354-1473
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产品特性
- Cynomolgus TRAIL R2 / DR5 / TNFRSF10B Protein, His Tag (MALS verified)
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1-1531) protein (His tag)
custom-made TOP2A 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1-1528) protein (His tag)custom-made TOP2A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1435-1531) protein (GST tag)TOP2A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 50 mM Tris, 0.5 M KCl, pH 8.0
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储存条件
- -80 °C
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- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
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别名
- TOP2A
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背景
- DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations.
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分子量
- 12.8 kDa
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NCBI登录号
- NP_001058
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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