Topoisomerase II alpha Protein (AA 1354-1473)
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- 抗原 See all Topoisomerase II alpha (TOP2A) 蛋白
- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1354-1473
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 序列
- AA 1354-1473
- 产品特性
- Cynomolgus TRAIL R2 / DR5 / TNFRSF10B Protein, His Tag (MALS verified)
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product TOP2A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 50 mM Tris, 0.5 M KCl, pH 8.0
- 储存条件
- -80 °C
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- 抗原
- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
- 别名
- TOP2A (TOP2A 产品)
- 背景
- DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations.
- 分子量
- 12.8 kDa
- NCBI登录号
- NP_001058
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
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