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Neuropilin 1 Protein (NRP1) (AA 22-644) (mFc Tag)

NRP1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN7013261
发货至: 中国
  • 抗原 See all Neuropilin 1 (NRP1) 蛋白
    Neuropilin 1 (NRP1)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 22-644
    宿主
    • 20
    • 7
    • 5
    • 1
    资源
    • 13
    • 11
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This Neuropilin 1 protein is labelled with mFc Tag.
    产品特性
    Human Neuropilin-1 / NRP1 / CD304 Protein, Mouse IgG2a Fc Tag (MALS verified)
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 0.1 EU per μg by the LAL method.
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    Discover our top product NRP1 蛋白
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  • 应用备注
    MALS verified
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
    储存条件
    -20 °C
  • 抗原
    Neuropilin 1 (NRP1)
    别名
    Neuropilin-1 (NRP1 产品)
    背景
    Neuropilin-1 (NRP1) is also known as Vascular endothelial cell growth factor 165 receptor (VEGF165R), CD antigen CD304, which belongs to the neuropilin family. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.
    分子量
    96.7 kDa
    途径
    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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