宿主: Human Coronavirus NL63 (HCoV-NL63)
宿主: Baculovirus infected Insect Cells
Recombinant
> 75 % as determined by SDS-PAGE.
限制
仅限研究用
状态
Lyophilized
缓冲液
PBS, pH 7.4
储存条件
-20 °C
抗原
HCoV-NL63 S1 Protein
物质类
Viral Protein
背景
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.