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GDF2 Protein (AA 320-429)

GDF2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN6973076
发货至: 中国
  • 抗原 See all GDF2 蛋白
    GDF2 (Growth Differentiation Factor 2 (GDF2))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 320-429
    宿主
    • 6
    • 3
    • 2
    资源
    • 7
    • 2
    • 2
    HEK-293 Cells
    产品特性
    Human GDF-2 Protein, Tag Free
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product GDF2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    ACN, TFA in Water
    储存条件
    -20 °C
  • 抗原
    GDF2 (Growth Differentiation Factor 2 (GDF2))
    别名
    GDF-2 (GDF2 产品)
    别名
    bmp9 Protein, BMP-9 Protein, BMP9 Protein, Bmp9 Protein, DSL1 Protein, growth differentiation factor 2 Protein, gdf2 Protein, GDF2 Protein, Gdf2 Protein
    背景
    Human Growth and differentiation factor 2 (GDF-2), also known as Bone morphogenetic protein 9 (BMP-9), is a member of the BMP subgroup of the TGF-beta superfamily proteins that signal through heterodimeric complexes composed of type I and type II BMP receptors. GDF-2 Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. ALK1 is a signalling receptor for bone morphogenetic protein-9 (BMP-9) in endothelial cells (ECs). BMP-9 bound with high affinity to ALK1 and endoglin, and weakly to the type-I receptor ALK2 and to the BMP type-II receptor (BMPR-II) and activin type-II receptor (ActR-II) in transfected COS cells. Binding of BMP-9 to ALK2 was greatly facilitated when BMPR-II or ActR-II were co-expressed.
    分子量
    12.1 kDa
    途径
    Transition Metal Ion Homeostasis
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