GDF2 Protein (AA 320-429)
This Recombinant GDF2 protein is expressed in HEK-293 Cells.
Quick Overview for GDF2 Protein (AA 320-429) (ABIN6973076)
抗原
See all GDF2 蛋白
GDF2
(Growth Differentiation Factor 2 (GDF2))
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
HEK-293 Cells
纯度
>95 % as determined by SDS-PAGE.
-
-
产品特性
- AA 320-429
-
产品特性
- Human GDF-2 Protein, Tag Free
-
内毒素水平
- Less than 1.0 EU per μg by the LAL method.
-
-
Growth Differentiation Factor 2 (GDF2) (AA 320-429) protein (His-IF2DI Tag)
GDF2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Growth Differentiation Factor 2 (GDF2) (AA 1-429) protein (GST tag)GDF2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- ACN, TFA in Water
-
储存条件
- -20 °C
-
-
- GDF2 (Growth Differentiation Factor 2 (GDF2))
-
别名
- GDF-2
-
背景
- Human Growth and differentiation factor 2 (GDF-2), also known as Bone morphogenetic protein 9 (BMP-9), is a member of the BMP subgroup of the TGF-beta superfamily proteins that signal through heterodimeric complexes composed of type I and type II BMP receptors. GDF-2 Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. ALK1 is a signalling receptor for bone morphogenetic protein-9 (BMP-9) in endothelial cells (ECs). BMP-9 bound with high affinity to ALK1 and endoglin, and weakly to the type-I receptor ALK2 and to the BMP type-II receptor (BMPR-II) and activin type-II receptor (ActR-II) in transfected COS cells. Binding of BMP-9 to ALK2 was greatly facilitated when BMPR-II or ActR-II were co-expressed.
-
分子量
- 12.1 kDa
-
途径
- Transition Metal Ion Homeostasis
抗原
-
You are here:
