GDF2 Protein (AA 320-429)
Quick Overview for GDF2 Protein (AA 320-429) (ABIN6973076)
抗原
See all GDF2 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 320-429
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产品特性
- Human GDF-2 Protein, Tag Free
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Growth Differentiation Factor 2 (GDF2) (AA 320-429) protein (His-IF2DI Tag)
GDF2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Growth Differentiation Factor 2 (GDF2) (AA 1-429) protein (GST tag)GDF2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 2 (GDF2) proteinGDF2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- ACN, TFA in Water
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储存条件
- -20 °C
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- GDF2 (Growth Differentiation Factor 2 (GDF2))
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别名
- GDF-2
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背景
- Human Growth and differentiation factor 2 (GDF-2), also known as Bone morphogenetic protein 9 (BMP-9), is a member of the BMP subgroup of the TGF-beta superfamily proteins that signal through heterodimeric complexes composed of type I and type II BMP receptors. GDF-2 Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. ALK1 is a signalling receptor for bone morphogenetic protein-9 (BMP-9) in endothelial cells (ECs). BMP-9 bound with high affinity to ALK1 and endoglin, and weakly to the type-I receptor ALK2 and to the BMP type-II receptor (BMPR-II) and activin type-II receptor (ActR-II) in transfected COS cells. Binding of BMP-9 to ALK2 was greatly facilitated when BMPR-II or ActR-II were co-expressed.
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分子量
- 12.1 kDa
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途径
- Transition Metal Ion Homeostasis
抗原
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