FGL1 Protein (AA 99-330) (Fc Tag)
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Quick Overview for FGL1 Protein (AA 99-330) (Fc Tag) (ABIN6964362)
抗原
See all FGL1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 99-330
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标记
- This FGL1 protein is labelled with Fc Tag.
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原理
- Recombinant Human FGL1 Protein with N-terminal human Fc tag
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特异性
- HFc(Glu99-Ala330) FGL1(Leu23-Ile312)
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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说明
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- FGL1 (Fibrinogen-Like 1 (FGL1))
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别名
- FGL1
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背景
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HFREP1,HP-041,HPS,LFIRE-1,LFIRE1
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008] -
分子量
- predicted molecular mass of 60.1 kDa after removal of the signal peptide. The apparent molecular mass of hFc-FGL1 is 55-70 kDa due to glycosylation.
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UniProt
- Q08830
抗原
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