CD1a Protein (CD1a) (AA 19-298) (Fc Tag)
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Quick Overview for CD1a Protein (CD1a) (AA 19-298) (Fc Tag) (ABIN6964179)
抗原
See all CD1a 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 19-298
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标记
- This CD1a protein is labelled with Fc Tag.
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原理
- Recombinant human CD1A protein with C-terminal human Fc tag
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特异性
- CD1A(Asp19-Ser298)+hFc(Glu99-Ala330)
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产品特性
- Extracellular Domain Protein
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纯化方法
- affinity purification
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CD1a (CD1a) (AA 19-300) (Active) protein (His tag)
CD1a 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD1a (CD1a) (AA 1-311) protein (GST tag)CD1a 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
CD1a (CD1a) (AA 19-300) protein (His tag)CD1a 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 85 % SDS
CD1a (CD1a) protein (Myc-DYKDDDDK Tag)CD1a 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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说明
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- CD1a
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别名
- CD1A
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背景
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R4, T6, CD1, FCB6, HTA1
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] -
分子量
- predicted molecular mass of 58.1 kDa after removal of the signal peptide.
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UniProt
- P06126
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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