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SLAMF6 Protein (AA 22-226) (His tag,mFc Tag)

This Recombinant SLAMF6 protein is expressed in HEK-293 Cells.
产品编号 ABIN6961121
发货至: 中国
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Quick Overview for SLAMF6 Protein (AA 22-226) (His tag,mFc Tag) (ABIN6961121)

抗原

See all SLAMF6 蛋白
SLAMF6 (SLAM Family Member 6 (SLAMF6))

蛋白类型

Recombinant

宿主

  • 18
  • 2
  • 1

资源

  • 11
  • 3
  • 2
  • 2
  • 2
  • 1
HEK-293 Cells

应用范围

Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

纯度

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • 产品特性

    AA 22-226

    标记

    This SLAMF6 protein is labelled with His tag,mFc Tag.

    原理

    Recombinant human NTB-A protein with C-terminal mouse Fc and 6xHis tag

    特异性

    NTB-A(Gln22-Met226) mFc(Pro99-Lys330) 6xHis tag

    产品特性

    Extracellular Domain Protein

    纯化方法

    Purified from cell culture supernatant by affinity chromatography
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  • 应用备注

    Extracellular Domain Proteins (ECD) can be used as:
    • Immunogens for antibody drug development
    • Reagents used for CAR-T positive cell monitoring
    • Reagents for antibody screening and functional testing
    • Reagents for antibody affinity measurement

    说明

    The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please see Certificate of Analysis for specific instructions of reconstitution.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    SLAMF6 (SLAM Family Member 6 (SLAMF6))

    别名

    NTB-A

    背景

    NTB-A,SLAMF6,Ly108,NK-T-B-antigen,CD352,KALI
    The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    分子量

    predicted molecular mass of 50.1 kDa after removal of the signal peptide.

    基因ID

    114836

    UniProt

    Q96DU3
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