SLAMF6 Protein (AA 22-226) (His tag,mFc Tag)
Our Local Distributor
北京 101111
Quick Overview for SLAMF6 Protein (AA 22-226) (His tag,mFc Tag) (ABIN6961121)
抗原
See all SLAMF6 蛋白蛋白类型
宿主
资源
应用范围
纯度
-
-
产品特性
- AA 22-226
-
标记
- This SLAMF6 protein is labelled with His tag,mFc Tag.
-
原理
- Recombinant human NTB-A protein with C-terminal mouse Fc and 6xHis tag
-
特异性
- NTB-A(Gln22-Met226) mFc(Pro99-Lys330) 6xHis tag
-
产品特性
- Extracellular Domain Protein
-
纯化方法
- Purified from cell culture supernatant by affinity chromatography
-
-
-
-
应用备注
-
Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
-
说明
-
The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
-
缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
有效期
- 12 months
-
-
- SLAMF6 (SLAM Family Member 6 (SLAMF6))
-
别名
- NTB-A
-
背景
-
NTB-A,SLAMF6,Ly108,NK-T-B-antigen,CD352,KALI
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms. -
分子量
- predicted molecular mass of 50.1 kDa after removal of the signal peptide.
-
基因ID
- 114836
-
UniProt
- Q96DU3
抗原
-