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CD38 Protein (AA 43-300) (Fc-His Tag)

This Recombinant CD38 protein is expressed in HEK-293 Cells.
产品编号 ABIN6961077
发货至: 中国

Quick Overview for CD38 Protein (AA 43-300) (Fc-His Tag) (ABIN6961077)

抗原

See all CD38 蛋白
CD38

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

应用范围

ELISA

纯度

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • 产品特性

    AA 43-300

    标记

    This CD38 protein is labelled with Fc-His Tag.

    原理

    Recombinant human CD38 protein with C-terminal human Fc and 6xHis tag

    特异性

    CD38 (Val43-Ile300) hFc (Glu99-Ala330) 6xHis tag

    产品特性

    Extracellular Domain Protein

    纯化方法

    Purified from cell culture supernatant by affinity chromatography
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 136,947.45 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 152,621.24 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    CD38

    背景

    CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2 . The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.

    分子量

    predicted molecular mass of 70-72 kDa after removal of the signal peptide.

    基因ID

    952

    UniProt

    P28907
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