CD38 Protein (AA 43-300) (Fc-His Tag)
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- 抗原 See all CD38 蛋白
- CD38
- 蛋白类型
- Recombinant
- 产品特性
- AA 43-300
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD38 protein is labelled with Fc-His Tag.
- 应用范围
- ELISA
- 原理
- Recombinant human CD38 protein with C-terminal human Fc and 6xHis tag
- 特异性
- CD38 (Val43-Ile300) hFc (Glu99-Ala330) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CD38 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CD38
- Abstract
- CD38 产品
- 背景
- CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2 . The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
- 分子量
- predicted molecular mass of 70-72 kDa after removal of the signal peptide.
- 基因ID
- 952
- UniProt
- P28907
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