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GDF15 Protein (AA 197-308) (His tag)

GDF15 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >90 % as determined by reduced SDS-PAGE.
产品编号 ABIN6952287
发货至: 中国
  • 抗原 See all GDF15 蛋白
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    蛋白类型
    Recombinant
    产品特性
    AA 197-308
    宿主
    • 14
    • 5
    • 3
    • 2
    • 1
    资源
    • 13
    • 8
    • 3
    • 1
    大肠杆菌(E. Coli)
    标记
    This GDF15 protein is labelled with His tag.
    序列
    AA 197-308
    纯度
    >90 % as determined by reduced SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product GDF15 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    60 % ACN, 0.085 % TFA
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    别名
    GDF-15 (GDF15 产品)
    别名
    GDF15 Protein, GDF-15 Protein, MIC-1 Protein, MIC1 Protein, NAG-1 Protein, PDF Protein, PLAB Protein, PTGFB Protein, SBF Protein, growth differentiation factor 15 Protein, GDF15 Protein, Gdf15 Protein
    背景
    Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1). Expression of MIC-1 mRNA in monocytoid cells is up-regulated by a variety of stimuli associated with activation, including interleukin 1β, tumor necrosis factor α (TNF-α), interleukin 2, and macrophage colony-stimulating factor but not interferon γ, or lipopolysaccharide (LPS). It is highly expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells, and vascular smooth muscle cells in normal and pathological condition. GDF-15 increases during tissue injury and inflammatory states and is associated with cardiometabolic risk. Increased GDF-15 levels are associated with cardiovascular diseases such as hypertrophy, heart failure, atherosclerosis, endothelial dysfunction, obesity, insulin resistance, diabetes, and chronic kidney diseases in diabetes. Increased GDF-15 level is linked with the progression and prognosis of the disease condition.
    分子量
    14.2 kDa
    NCBI登录号
    NP_004855
    途径
    SARS-CoV-2 Protein Interactome
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