GDF15 Protein (AA 197-308) (His tag)
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Quick Overview for GDF15 Protein (AA 197-308) (His tag) (ABIN6952287)
抗原
See all GDF15 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 197-308
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标记
- This GDF15 protein is labelled with His tag.
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序列
- AA 197-308
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Growth Differentiation Factor 15 (GDF15) (AA 197-308) (Active) protein (His tag)
GDF15 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Bis-Tris PAGE Active
Growth Differentiation Factor 15 (GDF15) (AA 197-308) (Active) protein (hFc Tag)GDF15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Growth Differentiation Factor 15 (GDF15) (AA 197-308) (Active) protein (hFc Tag,Biotin)GDF15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Growth Differentiation Factor 15 (GDF15) (AA 193-308) (Active) protein (His tag)GDF15 宿主: Cynomolgus 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Bis-Tris PAGE Active
Growth Differentiation Factor 15 (GDF15) (AA 197-307) (Active) protein (His tag)GDF15 宿主: 犬 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Bis-Tris PAGE Active
Growth Differentiation Factor 15 (GDF15) (AA 197-308) (Active) protein (hFc Tag,Biotin)GDF15 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Growth Differentiation Factor 15 (GDF15) (AA 189-303) (Active) protein (hFc Tag,Biotin)GDF15 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Growth Differentiation Factor 15 (GDF15) (AA 197-308) (Active) protein (Biotin,His-Avi Tag)GDF15 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Bis-Tris PAGE Active
Growth Differentiation Factor 15 (GDF15) (AA 31-308) protein (GST tag)GDF15 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 60 % ACN, 0.085 % TFA
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注意事项
- Please avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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- GDF15 (Growth Differentiation Factor 15 (GDF15))
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别名
- GDF-15
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背景
- Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1). Expression of MIC-1 mRNA in monocytoid cells is up-regulated by a variety of stimuli associated with activation, including interleukin 1β, tumor necrosis factor α (TNF-α), interleukin 2, and macrophage colony-stimulating factor but not interferon γ, or lipopolysaccharide (LPS). It is highly expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells, and vascular smooth muscle cells in normal and pathological condition. GDF-15 increases during tissue injury and inflammatory states and is associated with cardiometabolic risk. Increased GDF-15 levels are associated with cardiovascular diseases such as hypertrophy, heart failure, atherosclerosis, endothelial dysfunction, obesity, insulin resistance, diabetes, and chronic kidney diseases in diabetes. Increased GDF-15 level is linked with the progression and prognosis of the disease condition.
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分子量
- 14.2 kDa
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NCBI登录号
- NP_004855
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途径
- SARS-CoV-2 Protein Interactome
抗原
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