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Quick Overview for CXCL10 Protein (AA 22-98) (ABIN6952220)
抗原
See all CXCL10 蛋白蛋白类型
生物活性
宿主
资源
应用范围
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产品特性
- AA 22-98
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序列
- VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP
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产品特性
- Recombinant Human CXCL10 (IP-10)
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内毒素水平
- <0.01 EU per 1μg of the protein by the LAL method
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Biological Activity Comment
- EC50 = 6.3 nM determined by Migration Assay in cells expressing recombinant CXCR3
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Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 27-91) protein (His tag)
CXCL10 宿主: Cynomolgus 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98) (Active) protein (His tag)CXCL10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98) protein (His-IF2DI Tag)CXCL10 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 1-98) protein (GST tag)CXCL10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98) protein (Fc Tag)CXCL10 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) proteinCXCL10 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) proteinCXCL10 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98), (full length) protein (His tag)CXCL10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) proteinCXCL10 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
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储存条件
- -20 °C,-80 °C
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储存方法
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
有效期
- 12 months
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- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
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别名
- CXCL10 (IP-10)
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背景
- CXCL10 (IP-10) was originally identified as an IFN-gamma-inducible gene in endothelial, fibroblasts and monocytes cells. IP-10 is considered a member of the CXC chemokine subfamily from its protein sequence which includes the four conserved cysteine residues present in CXC chemokines. IP-10 signals through the CXCR3 receptor to selectively attract Th1 lymphocytes and monocytes. It also has angiostatic and mitogenic properties on vascular smooth muscle cells. A diverse population of cell types rapidly increases transcription of mRNA encoding IP-10, which suggests that gamma-induced protein may be a key mediator of the IFNG/IFN-gamma response.
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分子量
- 8.646 kDa
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UniProt
- P02778
抗原
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