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CCL27 Protein (AA 25-112)

This Recombinant CCL27 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN6952170
发货至: 中国

Quick Overview for CCL27 Protein (AA 25-112) (ABIN6952170)

抗原

See all CCL27 蛋白
CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 5
  • 4

资源

  • 8
  • 1
大肠杆菌(E. Coli)

应用范围

Cell Migration Assay (CMA)

纯度

> 97 % by SDS PAGE
  • 产品特性

    AA 25-112

    序列

    FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG

    产品特性

    Recombinant Human CCL27 (CTACK)

    内毒素水平

    <0.01 EU per 1μg of the protein by the LAL method

    Biological Activity Comment

    EC50 = 34 nM determined by Migration Assay in cells expressing recombinant CCR10
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water

    储存条件

    -20 °C,-80 °C

    储存方法

    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.

    有效期

    12 months
  • 抗原

    CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))

    别名

    CCL27 (CTACK)

    背景

    Cutaneous T-cell-attracting chemokine (CTACK/CCL27) is a ligand for cell surface receptor CCR10. It is responsible for chemotaxis of skin-homing memory T cells during cutaneous inflammation. Interestingly, after CCR10-mediated internalization, CTACK, as well as a non-secreted splice variant of the same gene, can reach the nucleus and modulate transcription and cell behavior.

    分子量

    10.149kDa

    UniProt

    Q9Y4X3
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