Quick Overview for CCL19 Protein (AA 22-98) (ABIN6952156)
抗原
See all CCL19 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 22-98
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序列
- GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS
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产品特性
- Recombinant Human CCL19 (MIP-3beta)
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内毒素水平
- <0.01 EU per 1μg of the protein by the LAL method
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Biological Activity Comment
- EC50 = 7.0 nM determined by Migration Assay with recombinant human CCR7
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Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) protein (T7 tag)
CCL19 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 26-108) protein (His tag)CCL19 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 1-98) protein (GST tag)CCL19 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) protein (Fc Tag)CCL19 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) (Active) protein (Biotin)CCL19 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 97 % by SDS PAGE CMA Active
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
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储存条件
- -20 °C,-80 °C
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储存方法
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
有效期
- 12 months
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- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
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别名
- CCL19 (MIP-3beta)
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背景
- Macrophage inflammatory protein-3-beta (MIP-3beta/CCL19), also known as EBI1 ligand chemokine (ELC), directs chemotaxis of dendritic cells, and certain B- and T- lymphocytes, but not monocytes or granulocytes. It is constituitively expressed in thymus and lymph nodes and binds specifically to target cells expressing the receptor CCR7. Being a homeostatic chemokine, its primary physiological role is considered to be in the normal recirculation and homing of lymphocyte. However, MIP-3beta could also be proinflammatory, and is implicated in the post-HIV infection responses.
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分子量
- 8.800 kDa
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UniProt
- Q99731
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途径
- Positive Regulation of Immune Effector Process
抗原
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