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CCL14 Protein (AA 28-93) (Biotin)

This Recombinant CCL14 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN6952143
发货至: 中国
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Quick Overview for CCL14 Protein (AA 28-93) (Biotin) (ABIN6952143)

抗原

See all CCL14 蛋白
CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))

蛋白类型

Recombinant

生物活性

Active

宿主

资源

  • 9
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大肠杆菌(E. Coli)

应用范围

Cell Migration Assay (CMA)

纯度

> 97 % by SDS PAGE
  • 产品特性

    AA 28-93

    标记

    This CCL14 protein is labelled with Biotin.

    序列

    GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN

    产品特性

    Biotininylated Recombinant Human CCL14 (HCC-1)

    内毒素水平

    <0.01 EU per 1μg of the protein by the LAL method

    Biological Activity Comment

    EC50 = 0.2-0.4 nM determined by migration assay with cells expressing recombinant CCR1
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water

    储存条件

    -20 °C,-80 °C

    储存方法

    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.

    有效期

    12 months
  • 抗原

    CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))

    别名

    CCL14 (HCC-1)

    背景

    Hemofiltrate CC chemokine-1(HCC-1/CCL14) is endogeneously expressed by numerous tissues. Upon processing of the N terminal residues of the full length HCC-1 by the uPA-plasmin system, the active form of HCC-1 (made by ChemoTactics) is a strong agonist for CCR1, CCR5 and to a lesser extent CCR3, and causes chemotaxis of different types of leukocytes. The active form of HCC-1 is also shown as a potent inhibitor of HIV entry.

    分子量

    10.220 kDa

    UniProt

    Q16627
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