IL-13 Protein (AA 21-132) (His tag,AVI tag,Biotin)
Quick Overview for IL-13 Protein (AA 21-132) (His tag,AVI tag,Biotin) (ABIN6950979)
抗原
See all IL-13 (IL13) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 21-132
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标记
- This IL-13 protein is labelled with His tag,AVI tag,Biotin.
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序列
- AA 21-132
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特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Interleukin 13 (IL13) (AA 21-132) protein (His-Avi Tag)
IL13 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Interleukin 13 (IL13) (AA 21-132) protein (Fc Tag)IL13 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 13 (IL13) (AA 19-132) protein (His tag)IL13 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 13 (IL13) (AA 26-131) (Active) protein (His tag)IL13 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 13 (IL13) (AA 21-132) protein (His-Avi Tag,Biotin)IL13 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Interleukin 13 (IL13) (AA 19-132) (Active) proteinIL13 宿主: 人 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 13 (IL13) (AA 21-132) (Active) protein (Fc Tag)IL13 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 (IL13) protein (mFc Tag)IL13 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Interleukin 13 (IL13) (AA 22-131) protein (His tag)IL13 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 13 (IL13) (Active) proteinIL13 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE Active
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说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. -
限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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注意事项
- Please avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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- IL-13 (IL13) (Interleukin 13 (IL13))
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别名
- IL-13
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背景
- Interleukin 13 (IL13) is also known as ALRH, BHR1and P600, is a single-chain glycosylated polypeptide, and is a cytokine critical in regulating inflammatory and immune responses. IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. IL-13 induces matrix metalloproteinases (MMPs) as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. IL-13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, which all contribute to airway obstruction.
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分子量
- 15.9 kDa
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NCBI登录号
- NP_002179
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
抗原
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