Integrin alpha 10 beta 1 (AA 23-1122) (Active) protein (His tag)
This Recombinant Integrin alpha 10 beta 1 protein is expressed in HEK-293 Cells.
产品编号 ABIN6938847
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Integrin alpha 10 beta 1 (AA 23-1122) (Active) protein (His tag) (ABIN6938847)
抗原
Integrin alpha 10 beta 1
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
HEK-293 Cells
纯度
>95 % as determined by SDS-PAGE.
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产品特性
- AA 23-1122
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标记
- His tag
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序列
- AA 23-1122
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 50 mM Tris, 150 mM NaCl, pH 7.5
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注意事项
- Please avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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- Integrin alpha 10 beta 1
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背景
- Human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types I-VI and laminin-1 in a Mg(2+)-dependent manner, whereas its binding to tenascin was only slightly better than to albumin. Alpha 10 beta 1 is a known collagen-binding I domain integrin, in addition to α1β1, α2β1 and α11β1. GROGER found in the N-terminal domain of collagens I and III, is only weakly recognised by α10β1, an important collagen receptor on chondrocytes, contrasting with the other collagen-binding integrins.
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分子量
- 126.6 kDa (ITGA10) & 83.7 kDa (ITGB1)
抗原
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