tau-441 (AA 1-441) protein (His tag)
This Recombinant protein is expressed in 大肠杆菌（E. Coli）.
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Quick Overview for tau-441 (AA 1-441) protein (His tag) (ABIN6809918)
抗原
tau-441
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
纯度
>90 % as determined by reduced SDS-PAGE.
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产品特性
- AA 1-441
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标记
- His tag
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH 7.5
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储存条件
- -20 °C
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- tau-441
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背景
- Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies. Tau-441 is known as "2N4R," "Isoform Tau-F," "Tau-4" or "Tau 441", which consisting of 441 amino acid. Tau-441 is a potential therapeutic target for pathogenesis.
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分子量
- 47.9 kDa
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NCBI登录号
- NP_005901
抗原
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