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IL-13 蛋白

This Recombinant IL-13 protein is expressed in 大肠杆菌(E. Coli).
Rockland
产品编号 ABIN6700025
Supplier Product No.: 009-001-v52-0100
发货至: 中国

Quick Overview for IL-13 蛋白 (ABIN6700025)

抗原

See all IL-13 (IL13) 蛋白
IL-13 (IL13) (Interleukin 13 (IL13))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

95,00%
  • Supplier Product No.

    009-001-v52-0100

    Supplier

    Rockland

    原理

    Human Interleukin-13 Recombinant Protein

    纯化方法

    Interleukin-13 purity was determined to be greater than 95% as determined by analysis by reducing and non-reducing SDS-pAGE.

    内毒素水平

    Measured by LAL is typically ≤ 1 EU/μg protein.

    Biological Activity Comment

    The activity is determined by the dose dependent proliferation of TF-1 cells and is typically less than 1 ng/mL.
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  • 应用备注

    Application Note: Interleukin-13 Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-Interleukin-13 in immunological assays.

    Other: User Optimized

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 100 μL

    浓度

    0.1 mg/mL

    缓冲液

    Buffer: 0.01 M Sodium Citrate, pH 3.0

    Stabilizer: None

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

    有效期

    6 months
  • 抗原

    IL-13 (IL13) (Interleukin 13 (IL13))

    别名

    IL13

    背景

    Synonyms: NC30

    Background: Interleukin-13 (IL-13) is an important cytokine secreted from Th2 cells. The functions attributed to IL-13 overlap significantly with those of IL-4 (induces IgE secretion from B cells and inhibits expression of inflammatory cytokines such as IL-1β, TNF-α, IL-8 and IL-6), but differs from IL-4 in that IL-13 seems to link inflammatory responses of immune cells to the pathophysiological changes in the surrounding non-immune cells. The receptor subunits of IL-13 consist of IL-4Rα, IL-13Rα1 and IL-13Rα2. Human and mouse IL-13 are cross-reactive. Recombinant human IL-13 is a non-glycosylated variant of native IL-13, containing 115 amino acids (additional Gln at position 113), with a molecular weight of 12.6 kDa.

    UniProt

    P35225

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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