Quick Overview for GDF15 蛋白 (ABIN6699908)
抗原
See all GDF15 蛋白蛋白类型
宿主
资源
应用范围
纯度
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Supplier Product No.
- 009-001-u95-0005
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Supplier
- Rockland
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原理
- Human Growth and Differentiation Factor-15 Recombinant Protein
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纯化方法
- Growth and Differentiation Factor-15 purity was determined to be greater than 95% as determined by analysis by HpLC, UV-Spectroscopy at 280nm and by reducing and non-reducing SDS-pAGE.
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内毒素水平
- Measured by LAL is typically ≤ 1 EU/μg protein.
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Biological Activity Comment
- The activity is determined by the inhibition of DU-145 cells and is typically 1-2 μg/mL.
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Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (His tag)
GDF15 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag)GDF15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 189-303) protein (Fc Tag)GDF15 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag,Biotin)GDF15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 193-308) protein (His tag)GDF15 宿主: Cynomolgus 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 189-303) protein (His tag)GDF15 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag)GDF15 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 197-307) protein (His tag)GDF15 宿主: 犬 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag,Biotin)GDF15 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 189-303) protein (Fc Tag,Biotin)GDF15 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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应用备注
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Application Note: Growth and Differentiation Factor-15 Recombinant Protein has been tested by SDS-PAGE and biological activity and is suitable as a control for polyclonal or monoclonal anti-Growth and Differentiation Factor-15 in immunological assays.
Other: User Optimized
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 50μL
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浓度
- 0.1 mg/mL
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缓冲液
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Buffer: 0.1 % Trifluoroacetic acid
Stabilizer: None
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
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有效期
- 6 months
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- GDF15 (Growth Differentiation Factor 15 (GDF15))
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别名
- GDF15
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背景
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Synonyms: MIC-1, Placental TGFβ, Prostate differentiation factor
Background: Growth and Differentiation Factor 15 (GDF-15) is a TGFβ family member, made by the placenta and heart tissues, that has a role in regulating inflammatory and apoptotic pathways. GDF-15 has become an immerging marker of early heart disease and has the potential as being used as a molecule for screening patients for early heart failure. Recombinant human GDF-15 is a non-glycosylated, disulfide linked homodimer, containing two identical 113 amino acid chains, with a total molecular weight of 24.5 kDa.
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UniProt
- Q99988
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途径
- SARS-CoV-2 Protein Interactome
抗原
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