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RCAN1 Protein (AA 1-117)

This Recombinant RCAN1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN667702
发货至: 中国
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Quick Overview for RCAN1 Protein (AA 1-117) (ABIN667702)

抗原

See all RCAN1 蛋白
RCAN1 (Regulator of Calcineurin 1 (RCAN1))

蛋白类型

Recombinant

宿主

  • 7
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资源

  • 4
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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

> 90 %
  • 产品特性

    AA 1-117

    序列

    MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGP GEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS

    产品特性

    DSCR1 isoform b, 1-117aa , Human, Recombinant, E.coli

    纯化方法

    > 90% by SDS-PAGE
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    20 mM Tris-HCl buffer ( pH 7.5) containing 0.1M NaCl, 1 mM DTT, 10 % Glycerol

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    RCAN1 (Regulator of Calcineurin 1 (RCAN1))

    别名

    Calcipressin-1/DSCR1

    背景

    The Down's syndrome candidate region 1 (DSCR1) protein, encoded by a gene located in the human chromosome 21, interacts with calcineurin and is overexpressed in Down's syndrome patients. DSCR1 Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A, possibly affecting central nervous system development. DSCR isoform b is shorter at the N-terminus compared to isoform a. Recombinant human DSCR1 was expressed in E. coli and purified by using conventional chromatography techniques.

    分子量

    13.2 kDa (117aa) confirmed by MALDI-TOF

    NCBI登录号

    NP_981962

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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