Quick Overview for RCAN1 Protein (AA 1-117) (ABIN667702)
抗原
See all RCAN1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 1-117
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序列
- MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGP GEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS
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产品特性
- DSCR1 isoform b, 1-117aa , Human, Recombinant, E.coli
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纯化方法
- > 90% by SDS-PAGE
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Regulator of Calcineurin 1 (RCAN1) (AA 1-252) protein (His tag)
custom-made RCAN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Regulator of Calcineurin 1 (RCAN1) (AA 1-197) protein (GST tag)RCAN1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Regulator of Calcineurin 1 (RCAN1) (AA 1-117), (Isoform B) proteinRCAN1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % pure SDS
Regulator of Calcineurin 1 (RCAN1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)RCAN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 20 mM Tris-HCl buffer ( pH 7.5) containing 0.1M NaCl, 1 mM DTT, 10 % Glycerol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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别名
- Calcipressin-1/DSCR1
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背景
- The Down's syndrome candidate region 1 (DSCR1) protein, encoded by a gene located in the human chromosome 21, interacts with calcineurin and is overexpressed in Down's syndrome patients. DSCR1 Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A, possibly affecting central nervous system development. DSCR isoform b is shorter at the N-terminus compared to isoform a. Recombinant human DSCR1 was expressed in E. coli and purified by using conventional chromatography techniques.
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分子量
- 13.2 kDa (117aa) confirmed by MALDI-TOF
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NCBI登录号
- NP_981962
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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