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GPX1(U49C) (AA 1-203) protein (His tag)

This Recombinant protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN667598
发货至: 中国

Quick Overview for GPX1(U49C) (AA 1-203) protein (His tag) (ABIN667598)

抗原

GPX1(U49C)

蛋白类型

Recombinant

宿主

资源

  • 1
大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

> 90 % by SDS - PAGE
  • 产品特性

    AA 1-203

    标记

    His tag

    产品特性

    GPX1(U49C), 1-203aa, Human, His tag, E.coli
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  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5mg/ml (determined by Bradford assay)

    缓冲液

    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 30% glycerol, 100mM NaCl

    储存条件

    4 °C
  • 抗原

    GPX1(U49C)

    别名

    GPX1 (U49C)

    背景

    GPX1 (Glutathione peroxidase 1) belongs to the glutathione peroxidase family, consisting of eight known glutathione peroxidases (Gpx1-8) in humans. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. The GPX1 is part of the enzymatic antioxidant defence, preventing oxidative damage to DNA, proteins and lipids by detoxifying hydrogen and lipid peroxides that may contribute to prostate cancer development. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. Recombinant human GPX1(U49C) protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Glutathione peroxidase 1, GSHPX1. NCBI no.: NP_000572

    分子量

    24.2kDa (223aa), confirmed by MALDI-TOF
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