ATF3 Protein (AA 1-181)
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- 抗原 See all ATF3 蛋白
- ATF3 (Activating Transcription Factor 3 (ATF3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-181
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- ATF3, 1-181aa, Human, E.coli
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ATF3 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20mM Tris-HCl, pH8.0, 2M Urea, 20%Glycerol
- 储存条件
- 4 °C
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- 抗原
- ATF3 (Activating Transcription Factor 3 (ATF3))
- 别名
- ATF3 (ATF3 产品)
- 别名
- zgc:55526 Protein, ATF3 Protein, LRG-21 Protein, LRF-1 Protein, LRFI Protein, atf-3 Protein, activating transcription factor 3 Protein, activating transcription factor 3 L homeolog Protein, atf3 Protein, ATF3 Protein, Atf3 Protein, atf3.L Protein
- 背景
- ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter. Synonyms: Activating transcription factor 3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, Cyclic AMP-dependent transcription factor ATF-3. NCBI no.: NP_001665
- 分子量
- 20.6kDa (181aa)
- 途径
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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