ATF3 Protein (AA 1-181)
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北京 101111
Quick Overview for ATF3 Protein (AA 1-181) (ABIN667497)
抗原
See all ATF3 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 1-181
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序列
- MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S
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产品特性
- ATF3, 1-181aa, Human, E.coli
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纯化方法
- > 90% by SDS-PAGE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 20 mM Tris-HCl buffer ( pH 8.0) containing 2M urea, 20 % glycerol
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注意事项
- Avoid repeated freezing and thawing cycles
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- ATF3 (Activating Transcription Factor 3 (ATF3))
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别名
- ATF3
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背景
- ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.
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分子量
- 20.6 kDa (181aa)
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NCBI登录号
- NP_001665
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途径
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
抗原
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