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ATF3 Protein (AA 1-181)

This Recombinant ATF3 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN667497
发货至: 中国
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Quick Overview for ATF3 Protein (AA 1-181) (ABIN667497)

抗原

See all ATF3 蛋白
ATF3 (Activating Transcription Factor 3 (ATF3))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

> 90 %
  • 产品特性

    AA 1-181

    序列

    MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S

    产品特性

    ATF3, 1-181aa, Human, E.coli

    纯化方法

    > 90% by SDS-PAGE
  • 想要此Protein的其他选项吗?

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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    20 mM Tris-HCl buffer ( pH 8.0) containing 2M urea, 20 % glycerol

    注意事项

    Avoid repeated freezing and thawing cycles

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    ATF3 (Activating Transcription Factor 3 (ATF3))

    别名

    ATF3

    背景

    ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.

    分子量

    20.6 kDa (181aa)

    NCBI登录号

    NP_001665

    途径

    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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