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NFNB (AA 1-217) protein (His tag)

宿主: E. coli 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN667164
发货至: 中国
  • 抗原
    NFNB
    蛋白类型
    Recombinant
    产品特性
    AA 1-217
    宿主
    E. coli
    资源
    • 1
    大肠杆菌(E. Coli)
    标记
    His tag
    应用范围
    SDS-PAGE (SDS)
    产品特性
    NFNB, 1-217aa, E.coli, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 50mM Nacl, 1mM DTT, 10% glycerol
    储存条件
    4 °C
  • 抗原
    NFNB
    背景
    NFNB, also known as NFSB, shows the ability to reduce quinines. This protein is an enzyme for activating prodrugs in antibody directed enzyme prodrug therapy. It also capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species. Recombinant E.coli NFNB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: dprA, nfsB, nfsI, ntr, dihydropteridine reductase, NAD(P)H-dependent, oxygen-insensitive. NCBI no.: NP_415110
    分子量
    26.0 kDa (237aa) confirmed by MALDI-TOF
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