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FKBP2 Protein (AA 22-142)

This Recombinant FKBP2 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN667129
发货至: 中国
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Quick Overview for FKBP2 Protein (AA 22-142) (ABIN667129)

抗原

See all FKBP2 蛋白
FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 10
  • 1

资源

  • 4
  • 2
  • 2
  • 1
  • 1
大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS), Enzyme Activity Assay (EAA)

纯度

> 90 %
  • 产品特性

    AA 22-142

    序列

    MATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL

    产品特性

    FKBP2, 22-142aa, Human, E.coli

    纯化方法

    > 90% by SDS-PAGE

    内毒素水平

    < 1 EU per 1ug of protein (determined by LAL method)

    Biological Activity Comment

    Specific activity is > 700nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmol of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 1 mM DTT

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

    别名

    FKBP13/FKBP2

    背景

    FKBP2 is peptidyl proline isomerase enzyme and a member of the immunophilin protein family. This protein is predominantly expressed in thymus and T cells and plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Recombinant FKBP2 protein was expressed in E. coli and purified by using conventional chromatography techniques.

    分子量

    13.4 kDa (122aa) confirmed by MALDI-TOF

    NCBI登录号

    NP_001128680
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