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Quick Overview for NCR1 Protein (AA 22-255) (ABIN666806)
抗原
See all NCR1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 22-255
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序列
- MQQQTLPKPF IWAEPHFMVP KEKQVTICCQ GNYGAVEYQL HFEGSLFAVD RPKPPERINK VKFYIPDMNS RMAGQYSCIY RVGELWSEPS NLLDLVVTEM YDTPTLSVHP GPEVISGEEV TFYCRLDTAT SMFLLLKEGR SSHVQRGYGK VQAEFPLGPV TTAHRGTYRC FGSYNNHAWS FPSEPVKLLV TGDIENTSLA PEDPTFPADT WGTYLLTTET GLQKDHALWD HTAQN
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产品特性
- NCR, NKp46 ( Extracellular Ig-like domain , 22-255aa, human), Recombinant, E.coli
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纯化方法
- > 95% by SDS-PAGE
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内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
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Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-255) (Active) protein (mFc Tag)
NCR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-254) (Active) protein (His tag)NCR1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-254) (Active) protein (His tag)NCR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-255) (Active) protein (hFc Tag)NCR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-255) (Active) protein (His tag)NCR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-254) (Active) protein (Biotin,His tag)NCR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-257) (Active) protein (His tag,AVI tag,Biotin)NCR1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Natural Cytotoxicity Triggering Receptor 1 (NCR1) protein (His tag)NCR1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-303) protein (GST tag)NCR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Natural Cytotoxicity Triggering Receptor 1 (NCR1) (AA 22-254) protein (Fc Tag)NCR1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol, 1 mM EDTA
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
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别名
- NKp46/NCR1
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背景
- A natural cytotoxicity receptor (NCR) NKp46 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. The three known NCRs include NKp46 and NKp30, which are expressed on circulating NKcells, and NKp44, which is expressed only on activating NK cells. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. NKp46 has two extracellular Ig-like domains followed by a ~40 residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. The extracellular Ig-like domain of NKp46 ( 22-255aa) was overexpressed in E. coli, and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer.
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分子量
- 26.6 kDa (235aa) confirmed by MALDI-TOF
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NCBI登录号
- NP_004820
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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