COMT Protein (AA 51-271)
Quick Overview for COMT Protein (AA 51-271) (ABIN666744)
抗原
See all COMT 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 51-271
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产品特性
- COMT, 51-271 aa, Human, Recombinant, E.coli
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Catechol-O-Methyltransferase (COMT) (AA 1-271) protein (His tag)
custom-made COMT 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catechol-O-Methyltransferase (COMT) (AA 1-265) protein (His tag)custom-made COMT 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catechol-O-Methyltransferase (COMT) (AA 51-271) protein (His tag)COMT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Catechol-O-Methyltransferase (COMT) (AA 1-182) protein (GST tag)COMT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/ml (determined by Bradford assay)
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缓冲液
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM MgCl2, 10% glycerol
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储存条件
- 4 °C
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- COMT (Catechol-O-Methyltransferase (COMT))
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别名
- COMT
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背景
- Catechol-O-methyltrasferase (COMT) is an enzyme that catalyses the transfer of the methyl group of S-adenosylmethionine (SAM) into catechol substrates such as levodopa, dopamine, epinephrine, and norepinephirine in the presence of Mg2+. COMT appears to be located in the postsynaptic neuron and plays roles in the metabolism of catechol estrogens and the inactivation of catecholamine neurotransmitters though enzymatic degradation. COMT inhibitors prevent levodopa degradation, increase its availability and are used in the treatment of patients with Parkinson's disease. Recombinant human COMT protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Catechol-O-methyltransferase , Catechol-O-methyltransferase , COMT. NCBI no.: NP_000745
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分子量
- 24.4 kDa (221 aa), confirmed by MALDI-TOF.
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途径
- Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
抗原
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