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Quick Overview for VSNL1 Protein (AA 1-191) (ABIN666662)
抗原
See all VSNL1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 1-191
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序列
- MGKQNSKLAP EVMEDLVKST EFNEHELKQW YKGFLKDCPS GRLNLEEFQQ LYVKFFPYGD ASKFAQHAFR TFDKNGDGTI DFREFICALS ITSRGSFEQK LNWAFNMYDL DGDGKITRVE MLEIIEAIYK MVGTVIMMKM NEDGLTPEQR VDKIFSKMDK NKDDQITLDE FKEAAKSDPS IVLLLQCDIQ K
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产品特性
- Visinin-like protein-1, 1-191 aa, Human, Recombinant, E.coli
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纯化方法
- > 95% by SDS-PAGE
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内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
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Visinin-Like 1 (VSNL1) (AA 1-191) protein (GST tag)
VSNL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Visinin-Like 1 (VSNL1) (AA 1-191) proteinVSNL1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS
Visinin-Like 1 (VSNL1) protein (Myc-DYKDDDDK Tag)VSNL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 20 mM Tris-HCl buffer ( pH 8.0) containing 1 mM DTT,10 % glycerol
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注意事项
- Avoid repeated freezing and thawing cycles
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- VSNL1 (Visinin-Like 1 (VSNL1))
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别名
- Visinin-like -1/VILIP
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背景
- Visinin-like protein-1, also known as VILIP-1, belongs to a family of neuronal calcium sensor proteins. VILIP-1 is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Also, it is expressed in pancreatic beta-cells. VILIP-1 elevation enhances insulin secretion in cAMP-associated manner. Down-regulation of VILIP-1 decreased cAMP accumulation but increased insulin gene transcription. Recombinant human Visinin-like protein-1 was expressed in E. coli and purified by using conventional chromatography.
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分子量
- 22.1 kDa (191aa) confirmed by MALDI-TOF
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NCBI登录号
- NP_003376
抗原
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