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Prolactin Protein (PRL) (AA 30-228)

This Recombinant Prolactin protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN5777732
发货至: 中国

Quick Overview for Prolactin Protein (PRL) (AA 30-228) (ABIN5777732)

抗原

See all Prolactin (PRL) 蛋白
Prolactin (PRL)

蛋白类型

Recombinant

生物活性

Active

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小鼠

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

> 90 % by SDS - PAGE
  • 产品特性

    AA 30-228

    序列

    MQPLPICSAG DCQTSLRELF DRVVILSHYI HTLYTDMFIE FDKQYVQDRE FMVKVINDCP TSSLATPEDK EQALKVPPEV LLNLILSLVQ SSSDPLFQLI TGVGGIQEAP EYILSRAKEI EEQNKQLLEG VEKIISQAYP EAKGNGIYFV WSQLPSLQGV DEESKILSLR NTIRCLRRDS HKVDNFLKVL RCQIAHQNNC

    内毒素水平

    < 1.0 EU per 1ug of protein (determined by LAL method)

    Biological Activity Comment

    Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 for this effect is less or equal 3 ng/ml.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Bioactivity Validated

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. In Phosphate buffered saline (  pH 7.4)

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原

    Prolactin (PRL)

    别名

    Prolactin

    背景

    Prolactin, also known as prl, is a hormone synthesized and secreted by lactotrope cells in the adenohypophysis (anterior pituitary gland). Prolactin has many effects, the most significant of which is to stimulate the mammary glands to produce milk (lactation). Increased serum prolactin during pregnancy causes enlargement of the mammary glands of the breasts and increases the production of milk. Recently, prolactin has demonstrated broader roles in breast cancer development, regulation of reproductive function, and immuno-regulation. Recombinant mouse Prolactin, was expressed in E.coli and purified by using conventional chromatography techniques.

    分子量

    22.7kDa (200aa) confirmed by MALDI-TOF

    NCBI登录号

    NP_035294

    UniProt

    Q9CPQ2

    途径

    JAK/STAT Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Protein targeting to Nucleus
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