Integrin beta 4 Protein (ITGB4) (AA 28-710) (His tag)
Quick Overview for Integrin beta 4 Protein (ITGB4) (AA 28-710) (His tag) (ABIN7281344)
抗原
See all Integrin beta 4 (ITGB4) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 28-710
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标记
- This Integrin beta 4 protein is labelled with His tag.
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序列
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NRCKKAPVKS CTECVRVDKD CAYCTDEMFR DRRCNTQAEL LAAGCQRESI VVMESSFQIT EETQIDTTLR RSQMSPQGLR VRLRPGEERH FELEVFEPLE SPVDLYILMD FSNSMSDDLD NLKKMGQNLA RVLSQLTSDY TIGFGKFVDK VSVPQTDMRP EKLKEPWPNS DPPFSFKNVI SLTEDVDEFR NKLQGERISG NLDAPEGGFD AILQTAVCTR DIGWRPDSTH LLVFSTESAF HYEADGANVL AGIMSRNDER CHLDTTGTYT QYRTQDYPSV PTLVRLLAKH NIIPIFAVTN YSYSYYEKLH TYFPVSSLGV LQEDSSNIVE LLEEAFNRIR SNLDIRALDS PRGLRTEVTS KMFQKTRTGS FHIRRGEVGI YQVQLRALEH VDGTHVCQLP EDQKGNIHLK PSFSDGLKMD AGIICDVCTC ELQKEVRSAR CSFNGDFVCG QCVCSEGWSG QTCNCSTGSL SDIQPCLREG EDKPCSGRGE CQCGHCVCYG EGRYEGQFCE YDNFQCPRTS GFLCNDRGRC SMGQCVCEPG WTGPSCDCPL SNATCIDSNG GICNGRGHCE CGRCHCHQQS LYTDTICEIN YSAIHPGLCE DLRSCVQCQA WGTGEKKGRT CEECNFKVKM VDELKRAEEV VVRCSFRDED DDCTYSYTME GDGAPGPNST VLVHKKKDCP PGS
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纯化方法
- > 90% by SDS-PAGE
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内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
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Integrin beta 4 (ITGB4) (AA 29-256) protein (His-IF2DI Tag)
ITGB4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Integrin beta 4 (ITGB4) (AA 28-137) protein (GST tag)ITGB4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Integrin beta 4 (ITGB4) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ITGB4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Integrin beta 4 (ITGB4)
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别名
- Integrin beta 4/CD104
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背景
- ITGB4, also known as integrin beta-4 isoform 1, is a member of the Integrin beta family. It forms noncovalent heterodimers with Integrin alpha 6 and participates in the formation of epithelial hemidesmosomes. This protein plays a critical structural role in the hemidesmosome of epithelial cells and is required for the regulation of keratinocyte polarity and motility. The heterodimer of them binds to NRG1 and this binding is essential for NRG1-ERBB signaling and binds to IGF1 and this binding is essential for IGF1 signaling. It tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Recombinant human ITGB4 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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分子量
- 77.5 kDa (691aa)
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NCBI登录号
- NP_000204
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途径
- Integrin Complex
抗原
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