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CD52 Protein (CD52) (AA 25-36) (hIgG-His-tag)

CD52 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
产品编号 ABIN6388178
发货至: 中国
  • 抗原 See all CD52 蛋白
    CD52
    蛋白类型
    Recombinant
    产品特性
    AA 25-36
    宿主
    • 11
    • 1
    资源
    • 8
    • 2
    • 1
    • 1
    Baculovirus infected Insect Cells
    标记
    This CD52 protein is labelled with hIgG-His-tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    GQNDTSQTSS PSLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H
    纯度
    > 95% by SDS-PAGE
    内毒素水平
    < 1 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product CD52 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原
    CD52
    别名
    CD52 (CD52 产品)
    背景
    CD52, also known as CAMPATH-1 antigen, is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein that is tethered to the cell surface with a GPI linkage. This protein can be targeted to induce immune suppression by complement-meditated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocytes-derived dendritic cells, eosinophils, and neutrophils, but not on the stem cells from which these lymphocytes were derived. Also, it is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. Recombinant human CD52, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    分子量
    28.2 kDa (251aa)
    NCBI登录号
    NP_001794
    UniProt
    P31358
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