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CD52 Protein (CD52) (AA 25-36) (hIgG-His-tag)

This Recombinant CD52 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN6388178
发货至: 中国

Quick Overview for CD52 Protein (CD52) (AA 25-36) (hIgG-His-tag) (ABIN6388178)

抗原

See all CD52 蛋白
CD52

蛋白类型

Recombinant

宿主

  • 12
  • 1

资源

  • 8
  • 3
  • 1
  • 1
Baculovirus infected Insect Cells

应用范围

SDS-PAGE (SDS)

纯度

> 95% by SDS-PAGE
  • 产品特性

    AA 25-36

    标记

    This CD52 protein is labelled with hIgG-His-tag.

    序列

    GQNDTSQTSS PSLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H

    内毒素水平

    < 1 EU per 1ug of protein (determined by LAL method)
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    CD52

    别名

    CD52

    背景

    CD52, also known as CAMPATH-1 antigen, is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein that is tethered to the cell surface with a GPI linkage. This protein can be targeted to induce immune suppression by complement-meditated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocytes-derived dendritic cells, eosinophils, and neutrophils, but not on the stem cells from which these lymphocytes were derived. Also, it is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. Recombinant human CD52, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

    分子量

    28.2 kDa (251aa)

    NCBI登录号

    NP_001794

    UniProt

    P31358
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