TARDBP Protein (AA 1-414)
Quick Overview for TARDBP Protein (AA 1-414) (ABIN7281189)
抗原
See all TARDBP 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 1-414
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序列
- MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA EPKHNSNRQL ERSGRFGGNP GGFGNQGGFG NSRGGGAGLG NNQGSNMGGG MNFGAFSINP AMMAAAQAAL QSSWGMMGML ASQQNQSGPS GNNQNQGNMQ REPNQAFGSG NNSYSGSNSG AAIGWGSASN AGSGSGFNGG FGSSMDSKSS GWGM
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TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (His tag)
custom-made TARDBP 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (His tag)custom-made TARDBP 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TAR DNA Binding Protein (TARDBP) protein (Myc-DYKDDDDK Tag)TARDBP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
TAR DNA Binding Protein (TARDBP) (AA 8-192) protein (His-IF2DI Tag)TARDBP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
TAR DNA Binding Protein (TARDBP) (AA 1-260) protein (His tag)TARDBP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (GST tag)TARDBP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
TAR DNA Binding Protein (TARDBP) (AA 1-260) protein (GST tag)TARDBP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (His tag)TARDBP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- Liquid. In 20 mM Tris-HCl( pH 8.0) containing 0.1M NaCl, 1 mM DTT, 1 mM EDTA, 10 % glycerol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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别名
- TDP-43/TARDBP
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背景
- TARDBP, as known as TAR DNA binding protein 43, was originally identified as a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. It has also been identified in individuals diagnosed with chronic traumatic encephalopathy, a condition that often mimics ALS and that has been associated with athletes who have experienced multiple concussions and other types of head injury. It has been shown to bind both DNA and RNA and have multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation. Recombinant human TARDBP protein was expressed in E. coli and purified by using conventional chromatography.
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分子量
- 44.7 kDa (414aa)
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NCBI登录号
- NP_031401
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UniProt
- Q13148
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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