NAD Nucleotidase 蛋白
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北京 101111
Quick Overview for NAD Nucleotidase 蛋白 (ABIN6253506)
抗原
蛋白类型
宿主
资源
纯度
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原理
- NAD Nucleotidase (H. influenzae) (rec.)
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特异性
- Full-length NAD 5'-nucleotidase (Haemophilus influenzae) without the signal peptide corresponding to the first 26 aa.
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产品特性
- Full-length NAD 5'-nucleotidase (Haemophilus influenzae) without the signal peptide corresponding to the first 26 aa.
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Biological Activity Comment
- With AMP: 856.4 nmol of Ade/min/mg of protein With NMN: 110,3 nmol of NR/min/mg of protein With NAD: 5.4 nmol of Ade/min per mg of protein | 5.3 nmol of NR/min/mg of protein
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- 0.5 mg/mL (Lot specific)
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浓度
- Lot specific
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缓冲液
- In 5 mM KH2PO4, pH 6.8 containing 100 mM TRIS-HCl ( pH 8.5) and 10 mM MgCl2.
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注意事项
- After opening, prepare aliquots and store at -80 °C.Avoid freeze/thaw cycles.
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储存条件
- -20 °C,-80 °C
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储存方法
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Short Term Storage: -20°C
Long Term Storage: -80°C
Use & Stability: Stable for at least 6 months after receipt when stored at -80°C.
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有效期
- 6 months
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- NAD Nucleotidase
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背景
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NadN, NAD Pyrophosphatase/5'-nucleotidase
NadN (NAD nucleotidase) is a periplasmic enzyme from Haemophilus influenzae, a major pathogen of the respiratory tract in humans that has developed the capability to exploit host NAD(P) for its nicotinamide dinucleotide requirement. NadN plays a central role by degrading NAD into adenosine and NR (nicotinamide riboside), NMN to nicotinamide riboside and AMP to adenosine. It shows a broad substrate specificity, recognizing either mono- or di-nucleotide nicotinamides and different adenosine phosphates with a maximal activity on 5'-adenosine monophosphate. It can be used as an economically alternative to produce NR (nicotinamide riboside). Catalytic activity: NAD=AMP + NMN=Ade+NR+PPi | AMP=Ade+Pi | NMN=NR+Pi
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分子量
- ~63.0kDa
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UniProt
- Q4QNY4
抗原
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