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PDGF-AA Homodimer 蛋白

This Recombinant PDGF-AA Homodimer protein is expressed in not_set.
产品编号 ABIN624786
发货至: 中国
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Quick Overview for PDGF-AA Homodimer 蛋白 (ABIN624786)

抗原

PDGF-AA Homodimer

蛋白类型

Recombinant

宿主

  • 7
  • 4
  • 2

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纯度

> 97.0 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
  • 序列

    The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Ile-Glu-Glu-Ala.

    产品特性

    Recombinant Human Platelet Derived Growth Factor-AA
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    The protein was lyophilized with no additives.It is recommended to reconstitute the lyophilized Platelet-derived Growth Factor-AA in sterile 18M -cm H 2 O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

    储存条件

    -20 °C
  • 抗原

    PDGF-AA Homodimer

    别名

    Platelet-Derived Growth Factor AA

    背景

    Platelet-Derived Growth Factor AA Human Recombinant is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 125 amino acids and having a total molecular mass of 28511 Dalton. PDGF-AA is purified by proprietary chromatographic techniques. Introduction: PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGF is stored in platelet alpha-granules and released upon platelet activation. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGF have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Synonyms: Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AA, PDGF-1.
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