PDGF-AA Homodimer 蛋白
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北京 101111
Quick Overview for PDGF-AA Homodimer 蛋白 (ABIN624786)
抗原
蛋白类型
宿主
宿主
纯度
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序列
- The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Ile-Glu-Glu-Ala.
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产品特性
- Recombinant Human Platelet Derived Growth Factor-AA
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- The protein was lyophilized with no additives.It is recommended to reconstitute the lyophilized Platelet-derived Growth Factor-AA in sterile 18M -cm H 2 O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
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储存条件
- -20 °C
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- PDGF-AA Homodimer
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别名
- Platelet-Derived Growth Factor AA
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背景
- Platelet-Derived Growth Factor AA Human Recombinant is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 125 amino acids and having a total molecular mass of 28511 Dalton. PDGF-AA is purified by proprietary chromatographic techniques. Introduction: PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGF is stored in platelet alpha-granules and released upon platelet activation. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGF have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Synonyms: Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AA, PDGF-1.
抗原
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