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AMBP 蛋白

This AMBP protein is expressed in Human.
产品编号 ABIN621846
发货至: 中国

Quick Overview for AMBP 蛋白 (ABIN621846)

抗原

See all AMBP 蛋白
AMBP (alpha 1 Microglobulin/bikunin precursor (AMBP))

宿主

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资源

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Human

纯度

> 98.0 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
  • 产品特性

    Human Urinary Trypsin Inhibitor
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a (1mg/ml) solution containing no additives.It is recommended to reconstitute the lyophilized UTI in sterile 18M omega cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

    储存条件

    -20 °C
  • 抗原

    AMBP (alpha 1 Microglobulin/bikunin precursor (AMBP))

    别名

    Urinary Trypsin Inhibitor

    背景

    Ulinastatin is derived from human urine. Introduction: Urinary-Trypsin Inhibitor is a glucoprotein proteinase inhibitor with a molecular weight of about 67,000 derived from human urine which inhibits the activity of trypsin, chymotrypsin, lactate, lipase, hyaluronidase and various pancreatic enzymes. Ulinastatin is effective for acute pancreatitis, chronic recurrent pancreatitis and hemorrhagic, traumatic and endotoxic shocks. Ulinastatin is has strong inhibition effect to various protease, sugar and fat hydrolase. Ulinastatin precursor is proteolytically processed into distinct functioning proteins. Urinary trypsin inhibitor belongs to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. Uristatin gene is located on chromosome 9 in a cluster of lipocalin genes. High levels of Ulinastatin secretion is an early marker of renal tubular involvement and has radical scavenging activity. Bikunin localizes cell membrane. Free uristatin and bikunin pass readily into urine and are primarily bound to heavy chains that constitute the proinhibitor form in plasma. Ulinastatin particularly interacts with ORF3 protein of hepatitis E virus and in charge for enhancing alpha microglobulin export from the hepatocyte. Synonyms: UTI, Bikunin, Uristatin, Ulinastatin, AMBP, EDC1, HI30, ITIL, IATIL, ITILC, Urinary Trypsin Inhibitor.
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