ASRGL1 蛋白
(1 reference)Quick Overview for ASRGL1 蛋白 (ABIN622163)
抗原
See all ASRGL1 蛋白适用
宿主
纯度
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产品特性
- L-Asparaginase
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Asparaginase Like 1 (ASRGL1) (AA 1-308) protein (His tag)
ASRGL1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Asparaginase Like 1 (ASRGL1) (AA 1-180) protein (GST tag)ASRGL1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Asparaginase Like 1 (ASRGL1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)ASRGL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Asparaginase Like 1 (ASRGL1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ASRGL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- The enzyme was lyophilized with no additives.
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储存条件
- -20 °C
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: "Gamma secretase inhibitors enhance vincristine-induced apoptosis in T-ALL in a NOTCH-independent manner." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 11, pp. 1616-26, (2014) (PubMed).
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: "Gamma secretase inhibitors enhance vincristine-induced apoptosis in T-ALL in a NOTCH-independent manner." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 11, pp. 1616-26, (2014) (PubMed).
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- ASRGL1 (Asparaginase Like 1 (ASRGL1))
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别名
- L-Asparaginase
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背景
- L-Asparaginase produced from E.Coli containing 303 amino acids and having a molecular mass of 31731 Dalton. Introduction: L-Asparaginase is an enzyme that depletes L-Asparagine ,an important nutrient for cancer cells, resulting in cancer/tumor cell starvation. L-asparaginase is an anti-tumor agent derived from E.coli.,which can inhibit the growth of malignant cells. It is used mainly for the induction of remission in acute lymphoblastic leukaemia. Because of the lymph node origin of malignant B cells in Multiple Myeloma, L-Asparagine is an essential amino acid for their cell metabolism, and, consequently, L-Asparaginase may be of value in managing the disease. The rationale behind asparaginase is that it takes advantage of the fact that ALL cellsare unable to synthesize the non-essential amino acidasparaginewhereas normal cells are able to make their own asparagine. These leukemic cells depend on circulating asparagine. Asparaginase however catalyzes the conversion of L-asparagine to aspartic acidand ammonia. This deprives the leukemic cell of circulating asparagine.
抗原
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