SPA 蛋白
SPA
宿主: Staphylococcus aureus
Recombinant
> 98.0 % as determined by RP-HPLC.
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- 抗原 See all SPA products
- SPA (Immunoglobulin G Binding Protein A (SPA))
- 蛋白类型
- Recombinant
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宿主
- Staphylococcus aureus
- 宿主
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- 产品特性
- Recombinant Staphylococcal Protein A
- 纯度
- > 98.0 % as determined by RP-HPLC.
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The protein solution contains no additives.
- 储存条件
- -20 °C
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- 抗原
- SPA (Immunoglobulin G Binding Protein A (SPA))
- 别名
- Staphylococcal Protein A (SPA 产品)
- 背景
- Recombinant Staphylococcal Protein A produced in E.Coli is a non-glycosylated, Polypeptide chain having a molecular mass of 45 kDa. Recombinant Staphylococcal Protein A is purified by proprietary chromatographic techniques. Introduction: Protein A is a cell wall protein deriving from Staphylococcus aureus which exhibits unique binding properties for IgG from a variety of mammalian species and for some IgM and IgA as well. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. It couples to a wide variety of reporter molecules including fluorescent dyes, enzyme markers, biotin, colloidal gold and radioactive iodine without affecting the antibody binding site. Recombinant Protein A was developed to increase the specificity of the molecule for IgG and is widely used both in research and bioprocessing. The recombinant protein A is produced by expressing a modified protein A gene in E.coli. A specific purification process with strict quality control was taken to get the recombinant protein A with the purity of more than 98% , no human IgG affinity step is used during validated fermentation and purification and devoid of bacterial contaminant found normally in native Protein A. (Free of Staphylococcus endotoxins and hemolysin). Synonyms: Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SPA.
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