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Aprotinin Protein (Aprotinin)

This Native Aprotinin protein is expressed in 牛.
产品编号 ABIN620215
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Aprotinin Protein (Aprotinin) (ABIN620215)

抗原

See all Aprotinin 蛋白
Aprotinin

蛋白类型

Native

宿主

  • 4
  • 2
Cow

资源

  • 3
  • 1
  • 1

纯度

> 98.0 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
  • 产品特性

    Native Bovine Aprotinin
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    The protein (1 mg/ml) was lyophilized with no additives.It is recommended to reconstitute the lyophilized Aprotinin in sterile 18M omega cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

    储存条件

    -20 °C
  • 抗原

    Aprotinin

    别名

    Aprotinin

    背景

    Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids {C 284 H 432 N 84 O 79 S 7 } arranged in a single polypeptide chain, cross-linked by three disulfide bridges and having a molecular mass of 6512. Introduction: Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b). Synonyms: Pancreatic trypsin inhibitor, Basic protease inhibitor, BPI, BPTI, Aprotinin, AP.
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