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CD33 Protein (CD33) (AA 18-259) (hIgG-His-tag)

This Recombinant CD33 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN5855022
发货至: 中国

Quick Overview for CD33 Protein (CD33) (AA 18-259) (hIgG-His-tag) (ABIN5855022)

抗原

See all CD33 蛋白
CD33

蛋白类型

Recombinant

宿主

  • 34
  • 4
  • 1
  • 1

资源

  • 29
  • 4
  • 3
  • 2
  • 2
Baculovirus infected Insect Cells

应用范围

SDS-PAGE (SDS)

纯度

> 90% by SDS-PAGE
  • 产品特性

    AA 18-259

    标记

    This CD33 protein is labelled with hIgG-His-tag.

    序列

    ADLDPNFWLQ VQESVTVQEG LCVLVPCTFF HPIPYYDKNS PVHGYWFREG AIISGDSPVA TNKLDQEVQE ETQGRFRLLG DPSRNNCSLS IVDARRRDNG SYFFRMERGS TKYSYKSPQL SVHVTDLTHR PKILIPGTLE PGHSKNLTCS VSWACEQGTP PIFSWLSAAP TSLGPRTTHS SVLIITPRPQ DHGTNLTCQV KFAGAGVTTE RTIQLNVTYV PQNPTTGIFP GDGSGKQETR AGVVHLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH

    内毒素水平

    < 1 EU per 1ug of protein (determined by LAL method)
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    CD33

    别名

    Siglec-3/CD33

    背景

    CD33, also known as myeloid cell surface antigen CD33 isoform 1, is a member of the Ig superfamily that is restricted to cells of the myelomonocytic lineage but whose functions and binding properties are unknown. It can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when it is expressed in a plasma membrane. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that are implicated in inhibition of cellular activity. It has been identified to modulate the risk of Alzheimer's disease (AD) in several recent genome-wide association studies (GWAS) in Caucasians. Recombinant human CD33, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

    分子量

    54 kDa (484aa)

    NCBI登录号

    NP_001763

    UniProt

    P20138
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