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Bestrophin 1 Protein (BEST1) (AA 292-585) (His tag)

BEST1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN5853599
发货至: 中国
  • 抗原 See all Bestrophin 1 (BEST1) 蛋白
    Bestrophin 1 (BEST1)
    蛋白类型
    Recombinant
    产品特性
    AA 292-585
    宿主
    • 6
    • 2
    资源
    • 2
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Bestrophin 1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSEQLINPF GEDDDDFETN WIVDRNLQVS LLAVDEMHQD LPRMEPDMYW NKPEPQPPYT AASAQFRRAS FMGSTFNISL NKEEMEFQPN QEDEEDAHAG IIGRFLGLQS HDHHPPRANS RTKLLWPKRE SLLHEGLPKN HKAAKQNVRG QEDNKAWKLK AVDAFKSAPL YQRPGYYSAP QTPLSPTPMF FPLEPSAPSK LHSVTGIDTK DKSLKTVSSG AKKSFELLSE SDGALMEHPE VSQVRRKTVE FNLTDMPEIP ENHLKEPLEQ SPTNIHTTLK DHMDPYWALE NRDEAHS
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product BEST1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Denatured

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    Bestrophin 1 (BEST1)
    别名
    BEST1 (BEST1 产品)
    别名
    CG6264 Protein, Dbest Protein, Dmel\\CG6264 Protein, anon-WO0118547.380 Protein, best Protein, dBest1 Protein, dbest1 Protein, dmBest1 Protein, BEST1 Protein, VMD2 Protein, best-1 Protein, ARB Protein, BEST Protein, BMD Protein, RP50 Protein, TU15B Protein, Bmd Protein, Vmd2 Protein, mBest1 Protein, Bestrophin 1 Protein, bestrophin 1 Protein, Best1 Protein, BEST1 Protein, best1 Protein, Bm1_25500 Protein
    背景
    BEST1 is a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Recombinant human BEST1 protein, fused to His-tag at N-terminus, was expressed in E.coli
    分子量
    36 kDa (317aa)
    NCBI登录号
    NP_004174
    UniProt
    O76090
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