Prohibitin 2 Protein (PHB2) (AA 1-299) (His tag)
This Recombinant Prohibitin 2 protein is expressed in 大肠杆菌（E. Coli）.
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Quick Overview for Prohibitin 2 Protein (PHB2) (AA 1-299) (His tag) (ABIN5853059)
抗原
See all Prohibitin 2 (PHB2) 蛋白
Prohibitin 2 (PHB2)
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
应用范围
SDS-PAGE (SDS)
纯度
> 85 % by SDS - PAGE
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产品特性
- AA 1-299
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标记
- This Prohibitin 2 protein is labelled with His tag.
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序列
- MGSSHHHHHH SSGLVPRGSH MGSMAQNLKD LAGRLPAGPR GMGTALKLLL GAGAVAYGVR ESVFTVEGGH RAIFFNRIGG VQQDTILAEG LHFRIPWFQY PIIYDIRARP RKISSPTGSK DLQMVNISLR VLSRPNAQEL PSMYQRLGLD YEERVLPSIV NEVLKSVVAK FNASQLITQR AQVSLLIRRE LTERAKDFSL ILDDVAITEL SFSREYTAAV EAKQVAQQEA QRAQFLVEKA KQEQRQKIVQ AEGEAEAAKM LGEALSKNPG YIKLRKIRAA QNISKTIATS QNRIYLTADN LVLNLQDESF TRGSDSLIKG KK
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Prohibitin 2 (PHB2) (AA 37-299) protein (GST tag)
PHB2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Prohibitin 2 (PHB2) (AA 1-299) protein (GST tag)PHB2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Denatured
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Prohibitin 2 (PHB2)
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别名
- PHB2
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背景
- PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases by similarity. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging. Recombinant human PHB2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
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分子量
- 35.7 kDa (322aa)
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NCBI登录号
- NP_001138303
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UniProt
- Q99623
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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