RCC1 蛋白
Our Local Distributor
北京 101111
Quick Overview for RCC1 蛋白 (ABIN5776891)
抗原
See all RCC1 蛋白蛋白类型
宿主
资源
纯度
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原理
- RCC1 (RanGEF), Regulator of Chromosome Condensation, Ran Guanine Exchange Factor, human, recombinant, E. coli
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied in 20 mM HEPES pH 7.650 mM NaCl and 2 mM DTE
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注意事项
- Please centrifuge briefly before opening (volume ≤2 ml).,avoid freeze/thaw cycles
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储存条件
- -80 °C
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储存方法
- store at -80 °C avoid freeze/thaw cycles
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有效期
- 12 months
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- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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别名
- RCC1 (RanGEF)
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背景
- RCC1 (Regulator of Chromosome Condensation, a β propeller chromatin-bound protein) catalyzes guanine nucleotide exchange of the Ras-related nuclear protein Ran. RCC1 is the guanine nucleotide exchange factor (GEF) for Ran which induces exchange between the bound GDP and cellular GTP. Genetic studies have suggested that RCC1 may be involved in sensing the replication state of DNA and controlling the activation of Cdc2/cyclin B protein kinase through Ran.
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分子量
- 44.97 kDa (421 amino acids)
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途径
- Chromatin Binding, Protein targeting to Nucleus
抗原
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